产品货号：
Z13237
中文名称：
CGAS抗体
英文名称：
Anti-CGAS Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 组分 | 50μL | 100μL | 150μL | 保存 |
| CGAS抗体(500μg/mL) | 50μL | 100μL | 150μL | -20℃ |
| WB抗体稀释液 | 5mL | 5mL | 5mL | 4℃ |
| IH抗体稀释液 | 5mL | 5mL | 5mL | 4℃ |
保存：-20℃，有效期1年，避免反复冻融，4℃可保存6个月。
| 抗体名称 | Anti-CGAS Antibody |
| 指标别名 | C6orf150;cGAS;Cyclic GMP-AMP synthase;h-cGAS;MB21D1 |
| 克隆性 | Polyclonal |
| 免疫原 | E.coli-derived human CGAS recombinant protein (Position:L208-F522). |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,ICC/IF,FCM,ELISA |
| 基因名称 | CGAS |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 实际分子量 | 62kD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | 抗原亲和纯化 |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| Uniprot ID | Q8N884 |
| 基因名全称 | Cyclic GMP-AMP synthase |
| 蛋白名全称 | Cyclic GMP-AMP synthase |
| 推荐稀释比 | Western blot(WB)：1:500～2000 ICC/IF：1:50～400 Flow cytometry (FCM)：1～3μg/1×106 cells ELISA：1:100～1000 |
| 背景资料 | cGAS (cyclic GMP-AMP synthase),also known as MB21D1 (Mab-21 domain containing 1),h-cGAS or C6orf150,is a 522 amino acid cytoplasmic nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (cGAMP) from ATP and GTP.cGAS is suggested to have antiviral activity by acting as a key cytosolic DNA sensor.cGAS binds to cytosolic DNA,which leads to cGAMP synthesis and activation of TMEM173,thereby trigger type-I interferon production.Expressed in monocytic cell line THP1,cGAS exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 6q13. |
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